Cathepsin Z Protein (CTSZ) (His tag)

Catalog No. ABIN7319393

This Recombinant Cathepsin Z protein is produced in Human Cells.

Quick Overview for Cathepsin Z Protein (CTSZ) (His tag) (ABIN7319393)

Target: Cathepsin Z (CTSZ)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Cathepsin Z protein is labelled with His tag.

Purpose: Recombinant Human Cathepsin Z Protein (His Tag)

Sequence: Gly24-Val303

Characteristics: Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Cathepsin Z (CTSZ)

Alternative Name: Cathepsin Z

Background:

Background: Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence, a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B, it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family, Cathepsin Z may be involved in tumorigenesis.

Synonym: Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ

Molecular Weight: 32.5 kDa

UniProt: Q9UBR2

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones