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CD14 Protein (CD14) (His tag)

CD14 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7194701
  • Target See all CD14 Proteins
    CD14
    Protein Type
    Recombinant
    Origin
    • 22
    • 5
    • 3
    • 1
    • 1
    • 1
    Rat
    Source
    • 15
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD14 protein is labelled with His tag.
    Purpose
    Recombinant Rat CD14 Protein (His Tag)
    Sequence
    Met1-Tyr341
    Characteristics
    A DNA sequence encoding the rat Cd14 (Q63691) (Met1-Tyr341) was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg protein as determined by the LAL method.
    Top Product
    Discover our top product CD14 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule Protein, CD14 antigen Protein, CD14 Protein, Cd14 Protein
    Background

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

    Synonym: CD14

    Molecular Weight
    36.7 kDa
    UniProt
    Q63691
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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