CD58 Protein (CD58) (Fc Tag)
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- Target See all CD58 Proteins
- CD58
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD58 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human LFA-3/CD58 Protein (Fc Tag)(Active)
- Sequence
- Met 1-Arg215
- Characteristics
- A DNA sequence encoding the human CD58 (Q9BRW0) (Met1-Arg215) was expressed with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- 1. Measured by its binding ability in a functional ELISA. Immobilized human CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.1 μg/ml.2. Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.10 μg/ml.
- Top Product
- Discover our top product CD58 Protein
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CD58 (CD58) (AA 29-215) protein (Fc Tag)
CD58 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD58 (CD58) (AA 1-240) protein (GST tag)CD58 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD58 (CD58) (AA 29-215) protein (His tag)CD58 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD58 (CD58) (AA 29-215) (Active) protein (Fc Tag)CD58 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD58
- Alternative Name
- LFA-3/CD58 (CD58 Products)
- Synonyms
- LFA-3 Protein, LFA3 Protein, ag3 Protein, CD58 molecule Protein, CD58 Protein
- Background
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Background: CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD295; LEPR; DB; OBR
- Molecular Weight
- 48.5 kDa
- UniProt
- Q9BRW0
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