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CD58 Protein (CD58) (His tag)

This Recombinant CD58 protein is expressed in Human Cells.
Catalog No. ABIN7319527

Quick Overview for CD58 Protein (CD58) (His tag) (ABIN7319527)

Target

See all CD58 Proteins
CD58

Protein Type

Recombinant

Origin

Human

Source

  • 8
  • 4
  • 2
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD58 protein is labelled with His tag.

    Purpose

    Recombinant Human LFA-3/CD58 Protein (His Tag)

    Sequence

    Phe29-Arg215(His147Tyr)

    Characteristics

    Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215(His147Tyr) is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD58

    Alternative Name

    LFA-3/CD58

    Background

    Background: Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

    Synonym: Lymphocyte Function-Associated Antigen 3, Surface Glycoprotein LFA-3, CD58, LFA3,Ag3, CD58 antigen

    Molecular Weight

    22.5 kDa

    UniProt

    P19256
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