CD58 Protein (CD58) (His tag)
Quick Overview for CD58 Protein (CD58) (His tag) (ABIN7319527)
Target
See all CD58 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
 - This CD58 protein is labelled with His tag.
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Purpose
 - Recombinant Human LFA-3/CD58 Protein (His Tag)
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Sequence
 - Phe29-Arg215(His147Tyr)
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Characteristics
 - Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215(His147Tyr) is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
 - < 1.0 EU per μg as determined by the LAL method.
 
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Restrictions
 - For Research Use only
 
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Format
 - Lyophilized
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Reconstitution
 - Please refer to the printed manual for detailed information.
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Buffer
 - Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Storage
 - 4 °C,-20 °C,-80 °C
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Storage Comment
 - Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 
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- CD58
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Alternative Name
 - LFA-3/CD58
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Background
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Background: Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Synonym: Lymphocyte Function-Associated Antigen 3, Surface Glycoprotein LFA-3, CD58, LFA3,Ag3, CD58 antigen
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Molecular Weight
 - 22.5 kDa
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UniProt
 - P19256
 
Target
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