CD68 Protein (His tag)
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- Target See all CD68 Proteins
- CD68 (CD68 Molecule (CD68))
- Protein Type
- Recombinant
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD68 protein is labelled with His tag.
- Purpose
- Recombinant Rat CD68/Macrosialin Protein (His Tag)
- Sequence
- Met1-Ser295
- Characteristics
- A DNA sequence encoding the rat CD68 (Q4FZY1) (Met1-Ser295) was expressed, fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product CD68 Protein
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CD68 Molecule (CD68) (AA 164-262) protein (GST tag)
CD68 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD68 Molecule (CD68) protein (Fc Tag)CD68 Origin: Rat Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
CD68 Molecule (CD68) (AA 22-319) protein (His tag)Crystallography grade CD68 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD68 Molecule (CD68) (AA 21-291) protein (His tag)Crystallography grade CD68 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD68 Molecule (CD68) (AA 22-354) protein (rho-1D4 tag)Crystallography grade CD68 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD68 Molecule (CD68) (AA 21-326) protein (rho-1D4 tag)Crystallography grade CD68 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD68 (CD68 Molecule (CD68))
- Alternative Name
- CD68/Macrosialin (CD68 Products)
- Synonyms
- Lamp4 Protein, Scard1 Protein, gp110 Protein, GP110 Protein, LAMP4 Protein, SCARD1 Protein, CD68 molecule Protein, CD68 antigen Protein, Cd68 molecule Protein, CD68 Protein, Cd68 Protein
- Background
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Background: Macrosialin, also known as CD68 and Gp110, is a single-pass type I membrane protein which belongs to the LAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Synonym: CD68
- Molecular Weight
- 30.9 kDa
- UniProt
- Q4FZY1
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