Quick Overview for CTLA4 Protein (Fc Tag) (ABIN7320970)
Target
See all CTLA4 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CTLA4 protein is labelled with Fc Tag.
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Purpose
- Recombinant Cynomolgus CTLA-4/CD152 Protein (Fc Tag)
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Sequence
- Ala37-Ser160
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Characteristics
- Recombinant Cynomolgus CTLA-4 is produced by our Mammalian expression system and the target gene encoding Ala37-Ser160 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) protein (His tag,mFc Tag)
CTLA4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) (Active) protein (Biotin,His-Avi Tag)CTLA4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) protein (Fc Tag)CTLA4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-160) (Active) protein (His tag)CTLA4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-162) (Active) protein (His tag)CTLA4 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) (Active) protein (His tag)CTLA4 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) (Active) protein (Fc Tag,AVI tag,Biotin)CTLA4 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-161) protein (His-DYKDDDDK-Strep II Tag)CTLA4 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (Active) protein (His tag)CTLA4 Origin: Guinea Pig Host: Yeast (Pichia pastoris) Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (Active) protein (His tag)CTLA4 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Alternative Name
- CTLA-4/CD152
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Background
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Background: Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Synonym: Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4
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Molecular Weight
- 40.2 kDa
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UniProt
- G7PL88
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Pathways
- Cancer Immune Checkpoints
Target
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