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DCK Protein (T7 tag,His tag)

DCK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318399
  • Target See all DCK Proteins
    DCK (Deoxycytidine Kinase (DCK))
    Protein Type
    Recombinant
    Origin
    • 9
    • 2
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This DCK protein is labelled with T7 tag,His tag.
    Purpose
    Recombinant Human Deoxycytidine Kinase/DCK Protein (His &T7 Tag)
    Sequence
    Met 1-Leu260
    Characteristics
    Recombinant Human Deoxycytidine Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu260 is expressed with a 6His, T7 tag at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DCK Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 7.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    DCK (Deoxycytidine Kinase (DCK))
    Alternative Name
    Deoxycytidine Kinase/DCK (DCK Products)
    Synonyms
    dck Protein, DCK Protein, wu:fc15f06 Protein, zgc:101771 Protein, dck1 Protein, deoxycytidine kinase Protein, deoxycytidine kinase, gene 2 L homeolog Protein, deoxycytidine kinase, gene 2 Protein, Deoxycytidine kinase Protein, deoxycytidine kinase, gene 1 L homeolog Protein, DCK Protein, dck Protein, dck.2.L Protein, dck.2 Protein, Dck Protein, FPV059 Protein, FPV151 Protein, dck.1.L Protein
    Background

    Background: Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.

    Synonym: Deoxycytidine Kinase, dCK, DCK

    Molecular Weight
    34.0 kDa
    UniProt
    P27707
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