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DCK Protein (T7 tag,His tag)

Recombinant DCK protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318399
$345.12
Plus shipping costs $50.00
Shipping to: United States
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Quick Overview for DCK Protein (T7 tag,His tag) (ABIN7318399)

Target

See all DCK Proteins
DCK (Deoxycytidine Kinase (DCK))

Protein Type

Recombinant

Origin

  • 12
  • 3
  • 1
  • 1
Human

Source

  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 90 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This DCK protein is labelled with T7 tag,His tag.

    Purpose

    Recombinant Human Deoxycytidine Kinase/DCK Protein (His &T7 Tag)

    Sequence

    Met 1-Leu260

    Characteristics

    Recombinant Human Deoxycytidine Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu260 is expressed with a 6His, T7 tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $12,595.45
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 7.5.

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    DCK (Deoxycytidine Kinase (DCK))

    Alternative Name

    Deoxycytidine Kinase/DCK

    Background

    Background: Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.

    Synonym: Deoxycytidine Kinase, dCK, DCK

    Molecular Weight

    34.0 kDa

    UniProt

    P27707
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