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ECH1 Protein

ECH1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319227
  • Target See all ECH1 Proteins
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human ECH1 Protein
    Sequence
    Thr34-Leu328
    Characteristics
    Recombinant Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial is produced by our E.coli expression system and the target gene encoding Thr34-Leu328 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,10 % Glycerol, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    Alternative Name
    ECH1 (ECH1 Products)
    Synonyms
    HPXEL Protein, Pxel Protein, AA617331 Protein, enoyl-CoA hydratase 1, peroxisomal Protein, enoyl CoA hydratase 1, peroxisomal Protein, enoyl-CoA hydratase 1 Protein, delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Protein, enoyl-CoA hydratase 1, peroxisomal L homeolog Protein, enoyl coenzyme A hydratase 1, peroxisomal Protein, ech1 Protein, ECH1 Protein, LOC747511 Protein, ech1.L Protein, Ech1 Protein
    Background

    Background: Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.

    Synonym: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial,ECH1,

    Molecular Weight
    34.5 kDa
    UniProt
    Q13011
    Pathways
    Monocarboxylic Acid Catabolic Process
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