EPH Receptor B2 Protein (EPHB2) (Fc Tag)

Catalog No. ABIN7318107

This Recombinant EPH Receptor B2 protein is expressed in Human Cells.

Quick Overview for EPH Receptor B2 Protein (EPHB2) (Fc Tag) (ABIN7318107)

Target: EPH Receptor B2 (EPHB2)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Human Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This EPH Receptor B2 protein is labelled with Fc Tag.

Purpose: Recombinant Human EphB2 Protein (Fc Tag)(Active)

Sequence: Val19-Ser482

Characteristics: Recombinant Human Ephrin type-B receptor 2 is produced by our Mammalian expression system and the target gene encoding Val19-Ser482 is expressed with a Fc tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human EphB2-Fc at 2μg/ml(100 μl/well) can bind Human EFNB2-His(Cat: PKSH032395).

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: EPH Receptor B2 (EPHB2)

Alternative Name: EphB2

Background:

Background: Ephrin type-B receptor 2(EPHB2) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHB2 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.

Synonym: CAPB,DRT,EK5,EPHT3,ERK,Hek5,PCBC,Tyro5,EPHB2,Ephrin type-B receptor 2

Molecular Weight: 78.5 kDa

Pathways: RTK Signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins