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EIF4E Protein

This Recombinant EIF4E protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318456

Quick Overview for EIF4E Protein (ABIN7318456)

Target

See all EIF4E Proteins
EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Protein Type

Recombinant

Origin

  • 10
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Human

Source

  • 9
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Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human EIF4E Protein

    Sequence

    Met 1-Val217

    Characteristics

    Recombinant Human Eukaryotic Translation Initiation Factor 4E is produced by our E.coli expression system and the target gene encoding Met1-Val217 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

    Alternative Name

    EIF4E

    Background

    Background: Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

    Synonym: Eukaryotic translation initiation factor 4E,eIF-4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein,EIF4E,EIF4EL1,EIF4F

    Molecular Weight

    25.1 kDa

    UniProt

    P06730

    Pathways

    BCR Signaling
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