FABP5 Protein

Catalog No. ABIN7317355

Recombinant FABP5 protein expressed in Escherichia coli (E. coli).

Quick Overview for FABP5 Protein (ABIN7317355)

Target: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 92 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human FABP5 Protein

Sequence: Met 1-Glu 135

Characteristics: A DNA sequence encoding the human FABP5 (Q01469) (Met 1-Glu 135) was expressed and purified.

Sterility: 0.2 μm filtered

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile 50 mM Tris, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

Alternative Name: FABP5

Background: E-FABP,Epidermal-Type Fatty Acid-Binding Protein,FABP5,Fatty Acid-Binding Protein 5,Fatty Acid-Binding Protein Epidermal,PA-FABP,Psoriasis-Associated Fatty Acid-Binding Protein Homolog,Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids, as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.

Molecular Weight: 15.2 kDa

Gene ID: 2171

UniProt: Q01469