FETUB Protein (His tag)

Catalog No. ABIN7320228

Recombinant FETUB protein expressed in HEK-293 Cells.

Quick Overview for FETUB Protein (His tag) (ABIN7320228)

Target: FETUB (Fetuin B (FETUB))

Protein Type: Recombinant

Origin: Mouse

Source: HEK-293 Cells

Purity: > 97 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This FETUB protein is labelled with His tag.

Purpose: Recombinant Mouse Fetuin-B/FETUB Protein (His Tag)

Sequence: Met 1-Pro 388

Characteristics: A DNA sequence encoding the extracellular domain of mouse FETUB (Q9QXC1-1) (Met 1-Pro 388) was expressed, with a polyhistidine tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: FETUB (Fetuin B (FETUB))

Alternative Name: Fetuin-B/FETUB

Background: 2310011O17Rik,AI255764,D17980,Gugu,Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption. Fetuin-A has been identified as a major protein during fetal life and is also involved in important functions such as protease inhibitory activities and development-associated regulation of calcium metabolism and osteogenesis. Fetuin-A is a key partner in the recovery phase of an acute inflammatory response. Fetuin-B / FETUB is found at least in human and rodents. It is unambiguously a paralogue of Fetuin-A. Fetuin-A and Fetuin-B exhibit significant differences at the amino acid sequence level, notably including variations with respect to the archetypal fetuin-specific signature.

Molecular Weight:

Calculated MW: 42.3 kDa

Observed MW: 55-60 kDa

UniProt: Q9QXC1