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Fibrillin 1 Protein (FBN1) (His tag)

FBN1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319692
  • Target See all Fibrillin 1 (FBN1) Proteins
    Fibrillin 1 (FBN1)
    Protein Type
    Recombinant
    Origin
    • 7
    • 6
    • 4
    Human
    Source
    • 14
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This Fibrillin 1 protein is labelled with His tag.
    Purpose
    Recombinant Human Fibrillin-1/FBN1 Protein (His Tag)
    Sequence
    Ser2732-His287
    Characteristics
    Recombinant Human Fibrillin-1 is produced by our Mammalian expression system and the target gene encoding Ser2732-His2871 is expressed with a 8His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product FBN1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Fibrillin 1 (FBN1)
    Alternative Name
    Fibrillin-1/FBN1 (FBN1 Products)
    Synonyms
    FBN1 Protein, ACMICD Protein, ECTOL1 Protein, FBN Protein, GPHYSD2 Protein, MASS Protein, MFS1 Protein, OCTD Protein, SGS Protein, SSKS Protein, WMS Protein, WMS2 Protein, AI536462 Protein, B430209H23 Protein, Fib-1 Protein, Tsk Protein, fibrillin 1 Protein, FBN1 Protein, Fbn1 Protein
    Background

    Background: Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.

    Synonym: Fibrillin-1, FBN1, Asprosin, FBN

    Molecular Weight
    17 kDa
    UniProt
    P35555
    Pathways
    Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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