FGF7 Protein (AA 32-194)

Catalog No. ABIN7318490

Recombinant FGF7 protein expressed in Escherichia coli (E. coli).

Quick Overview for FGF7 Protein (AA 32-194) (ABIN7318490)

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 32-194

Purpose: Recombinant Human FGF-7/KGF Protein

Sequence: Cys32-Thr194

Characteristics: Recombinant Human Fibroblast Growth Factor 7/Keratinocyte growth factor is produced by our E.coli expression system and the target gene encoding Cys32-Thr194 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,1 mM EDTA,5 % Trehalose, 0.02 % Tween 80, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Alternative Name: FGF-7/KGF

Background: FGF-7,FGF7,Fibroblast growth factor 7,HBGF-7,Heparin-binding growth factor 7,KGF,Keratinocyte growth factor,Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.

Molecular Weight:

Calculated MW: 18.9 kDa

Observed MW: 17 kDa

Gene ID: 2252

UniProt: P21781

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway