GALK1 Protein (His-GST)
Quick Overview for GALK1 Protein (His-GST) (ABIN7195881)
Target
See all GALK1 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This GALK1 protein is labelled with His-GST.
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Purpose
- Recombinant Human GALK1/Galactokinase Protein (His & GST Tag)
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Sequence
- Met 1-Leu 392
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Characteristics
- A DNA sequence encoding the human GALK1 (P51570) (Met 1-Leu 392) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 2 mM GSH, pH 8.0
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- GALK1 (Galactokinase 1 (GALK1))
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Alternative Name
- GALK1/Galactokinase
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Background
- GALK,GALK1,Galactokinase,Galactose Kinase,Galactokinase, also known as Galactose kinase, GALK and GALK1, is a protein which belongs to theGHMP kinase family and GalK subfamily. Galactokinase / GALK1 is a major enzyme for galactose metabolism. Galactokinase (GALK) deficiency is an autosomal recessive disorder characterized by elevation of blood galactose concentration and diminished galactose-1-phosphate, leading to the production of galactitol. Defects in GALK1 are the cause of galactosemia II ( GALCT2 ) which II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.
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Molecular Weight
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Calculated MW: 70.0 kDa
Observed MW: 60 kDa
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Gene ID
- 2584
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UniProt
- P51570
Target
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