GMFB Protein

Catalog No. ABIN7317274

This Recombinant GMFB protein is expressed in Escherichia coli (E. coli).

Quick Overview for GMFB Protein (ABIN7317274)

Target: GMFB (Glia Maturation Factor, beta (GMFB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human GMFB Protein

Sequence: Met 1-His142

Characteristics: A DNA sequence encoding the human GMFB (Met1-His142) was expressed.

Sterility: 0.2 μm filtered

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: GMFB (Glia Maturation Factor, beta (GMFB))

Alternative Name: GMFB

Background: GMF,GMF-beta,Glia maturation factor beta,GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.

Molecular Weight:

Calculated MW: 16.7 kDa

Observed MW: 17 kDa

Gene ID: 2764

NCBI Accession: NP_004115

UniProt: P60983