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GMFB Protein (His tag)

GMFB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318532
  • Target See all GMFB products
    GMFB (Glia Maturation Factor, beta (GMFB))
    Protein Type
    Recombinant
    Origin
    • 10
    • 2
    • 1
    Human
    Source
    • 9
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GMFB protein is labelled with His tag.
    Purpose
    Recombinant Human GMFB Protein (His Tag)
    Sequence
    Met 1-His142
    Characteristics
    Recombinant Human Glia maturation factor beta is produced by our E.coli expression system and the target gene encoding Met1-His142 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,200 mMNaCl, pH 8.0.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    GMFB (Glia Maturation Factor, beta (GMFB))
    Alternative Name
    GMFB (GMFB Products)
    Synonyms
    fc25b01 Protein, zgc:56451 Protein, zgc:86831 Protein, wu:fa97c03 Protein, wu:fc25b01 Protein, GMFB Protein, DKFZp459J101 Protein, gmfb Protein, 3110001H22Rik Protein, 3110001O16Rik Protein, AI851627 Protein, C79176 Protein, D14Ertd630e Protein, GMF Protein, gmf-beta Protein, glia maturation factor, beta Protein, glia maturation factor beta Protein, Glia maturation factor beta Protein, glia maturation factor, beta L homeolog Protein, gmfb Protein, GMFB Protein, Gmfb Protein, EDI_093190 Protein, Tsp_04922 Protein, LOC100101176 Protein, gmfb.L Protein
    Background

    Background: Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.

    Synonym: Glia maturation factor beta,GMF-beta, GMF

    Molecular Weight
    17.7 kDa
    UniProt
    P60983
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