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GCDH Protein (His tag)

GCDH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318540
  • Target See all GCDH Proteins
    GCDH (Glutaryl-CoA Dehydrogenase (GCDH))
    Protein Type
    Recombinant
    Origin
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GCDH protein is labelled with His tag.
    Purpose
    Recombinant Human GCDH Protein (His Tag)
    Sequence
    Arg45-Lys438
    Characteristics
    Recombinant Human Glutaryl-CoA Dehydrogenase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg45-Lys438 is expressed with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product GCDH Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    GCDH (Glutaryl-CoA Dehydrogenase (GCDH))
    Alternative Name
    GCDH (GCDH Products)
    Synonyms
    ACAD5 Protein, GCD Protein, zgc:56505 Protein, zgc:77704 Protein, 9030411L18 Protein, AI266902 Protein, D17825 Protein, glutaryl-CoA dehydrogenase Protein, glutaryl-CoA dehydrogenase a Protein, glutaryl-Coenzyme A dehydrogenase Protein, GCDH Protein, Gcdh Protein, gcdha Protein
    Background

    Background: Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.

    Synonym: Glutaryl-CoA Dehydrogenase Mitochondrial, GCD, GCDH

    Molecular Weight
    45.0 kDa
    UniProt
    Q92947
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