GZMB Protein (His tag)
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- Target See all GZMB Proteins
- GZMB (Granzyme B (GZMB))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Human Cells
- Purification tag / Conjugate
- This GZMB protein is labelled with His tag.
- Purpose
- Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)
- Sequence
- Gly19-Ser247
- Characteristics
- Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.
- Purity
- > 85 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GZMB Protein
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Granzyme B (GZMB) (AA 21-247) protein (GST tag)
GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 148-247) protein (GST tag)GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 1-247) protein (GST tag)GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 21-247) protein (His tag)Crystallography grade GZMB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Granzyme B (GZMB) (AA 21-247) protein (His tag)Crystallography grade GZMB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- Granzyme B/GZMB (GZMB Products)
- Synonyms
- CCPI Protein, CGL-1 Protein, CGL1 Protein, CSP-B Protein, CSPB Protein, CTLA1 Protein, CTSGL1 Protein, HLP Protein, SECT Protein, granzyme B Protein, GZMB Protein
- Background
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Background: Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Synonym: Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1
- Molecular Weight
- 26.5 kDa
- UniProt
- P04187
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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