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IL-10 Protein

This Recombinant IL-10 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7320571

Quick Overview for IL-10 Protein (ABIN7320571)

Target

See all IL-10 (IL10) Proteins
IL-10 (IL10) (Interleukin 10 (IL10))

Protein Type

Recombinant

Origin

  • 26
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Mouse

Source

  • 31
  • 22
  • 17
  • 11
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Escherichia coli (E. coli)

Purity

> 95 % as determined by SDS-PAGE
  • Purpose

    Recombinant Mouse Interleukin-10/IL-10 Protein

    Sequence

    Ser19-Ser178

    Characteristics

    Recombinant Mouse Interleukin-10 is produced by our E.coli expression system and the target gene encoding Ser19-Ser178 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    IL-10 (IL10) (Interleukin 10 (IL10))

    Alternative Name

    Interleukin-10/IL-10

    Background

    Background: Mouse Il10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. Many viruses encode viral members of the IL-10 family, such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV).Its main function is inhibiting the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. Although human and mouse IL-10 are 81 % identical at the nucleotide and amino acid level, mouse IL-10 is species-specific and does not act on human cells. Interestingly, Human IL-10 is active on mouse cells.

    Synonym: Interleukin-10,Il10,IL-10,Cytokine synthesis inhibitory factor,CSIF,

    Molecular Weight

    18.9 kDa

    UniProt

    P18893

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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