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IL17F Protein

This Recombinant IL17F protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318651

Quick Overview for IL17F Protein (ABIN7318651)

Target

See all IL17F Proteins
IL17F (Interleukin 17F (IL17F))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 15
  • 7
  • 5
  • 2
  • 1
Human

Source

  • 9
  • 9
  • 4
  • 3
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human Interleukin-17F/IL-17F Protein (Active)

    Sequence

    Arg31-Gln163

    Characteristics

    Recombinant Human Interleukin-17F is produced by our E.coli expression system and the target gene encoding Arg31-Gln163 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 5-40 ng/ml.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    IL17F (Interleukin 17F (IL17F))

    Alternative Name

    Interleukin-17F/IL-17F

    Background

    Background: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.

    Synonym: Interleukin-17F, IL-17F, Cytokine ML-1, Interleukin-24, IL-24, IL17F, IL24

    Molecular Weight

    15 kDa

    UniProt

    Q96PD4

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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