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IL-8 Protein

This Recombinant IL-8 protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN7318687

Quick Overview for IL-8 Protein (ABIN7318687)

Target

See all IL-8 (IL8) Proteins
IL-8 (IL8) (Interleukin 8 (IL8))

Protein Type

Recombinant

Origin

  • 29
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 36
  • 13
  • 11
  • 4
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purpose

    Recombinant Human IL-8/CXCL8 Protein (aa 28-99)

    Sequence

    Ser28-Ser99

    Characteristics

    Recombinant Human Interleukin-8 is produced by our E.coli expression system and the target gene encoding Ser28-Ser99 is expressed.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    IL-8 (IL8) (Interleukin 8 (IL8))

    Alternative Name

    IL-8/CXCL8

    Background

    Background: Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.

    Synonym: Interleukin-8, IL-8, C-X-C Motif Chemokine 8, Emoctakin, Granulocyte Chemotactic Protein 1, GCP-1, Monocyte-Derived Neutrophil Chemotactic Factor, MDNCF, Monocyte-Derived Neutrophil-Activating Peptide, MONAP, Neutrophil-Activating Protein 1, NAP-1, Protein 3-10C, T-Cell Chemotactic Factor, GCP1,IL8,Interleukin-8,LECT,LUCT,LYNAP,MDNCF,MONAP,NAF,NAP-1,NAP1

    Molecular Weight

    8.5 kDa

    UniProt

    P10145

    Pathways

    TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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