Kallikrein 5 Protein (KLK5) (His tag)

Catalog No. ABIN7318699

This Recombinant Kallikrein 5 protein is expressed in Human Cells.

Quick Overview for Kallikrein 5 Protein (KLK5) (His tag) (ABIN7318699)

Target: Kallikrein 5 (KLK5)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This Kallikrein 5 protein is labelled with His tag.

Purpose: Recombinant Human Kallikrein 5/KLK5 Protein (His Tag)

Sequence: Val23-Ser293

Characteristics: Recombinant Human Kallikrein 5 is produced by our Mammalian expression system and the target gene encoding Val23-Ser293 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, 10 % Glycerol, pH 5.5.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: Kallikrein 5 (KLK5)

Alternative Name: Kallikrein 5/KLK5

Background:

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Synonym: Kallikrein-5, Kallikrein-Like Protein 2, KLK-L2, Stratum Corneum Tryptic Enzyme, KLK5, SCTE

Molecular Weight: 30.7 kDa

UniProt: Q9Y337

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling