Quick Overview for Notch1 Protein (His tag) (ABIN7320796)
Target
See all Notch1 (NOTCH1) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Notch1 protein is labelled with His tag.
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Purpose
- Recombinant Mouse Motch A/NOTCH1 Protein (His Tag)
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Sequence
- Ala18-Gln526
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Characteristics
- Recombinant Mouse Notch 1 is produced by our Mammalian expression system and the target gene encoding Ala18-Gln526 is expressed with a 6His tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Notch 1 (NOTCH1) (AA 19-526) (Active) protein (His-Avi Tag)
NOTCH1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Notch 1 (NOTCH1) (AA 19-526) (Active) protein (Biotin,His-Avi Tag)NOTCH1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Notch 1 (NOTCH1) (AA 23-132) protein (GST tag)NOTCH1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Notch 1 (NOTCH1) (AA 2309-2555) protein (His tag)NOTCH1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Notch 1 (NOTCH1) (Active) protein (His tag)NOTCH1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 82 % as determined by SDS-PAGE Active
Notch 1 (NOTCH1) (AA 19-526) (Active) protein (His tag)NOTCH1 Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Notch 1 (NOTCH1) (AA 19-526) (Active) protein (Fc Tag)NOTCH1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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Alternative Name
- Motch A/NOTCH1
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Background
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Background: Mouse Notch1 is a 300 kDa type I transmembrane glycoprotein and it functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Mouse Notch1 is synthesized as a 2531 amino acid (aa) precursor that contains an 18 aa signal sequence, a 1707 aa extracellular domain (ECD) with 36 EGFlike repeats and three Lin12/notch repeats, a 21 aa transmembrane segment and a 785 aa cytoplasmic domain that contains six ankyrin repeats, a glutamine-rich domain and a PEST sequence. Notch1 may play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation and may be involved in mesoderm development, somite formation and neurogenesis.
Synonym: Neurogenic locus notch homolog protein 1, Notch 1, Motch A, Mt14,lin-12,Mis6,N1,Tan1
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Molecular Weight
- 54.4 kDa
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UniProt
- Q01705
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Pathways
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Target
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