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PON3 Protein (His tag)

PON3 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317316
  • Target See all PON3 Proteins
    PON3 (Paraoxonase 3 (PON3))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This PON3 protein is labelled with His tag.
    Purpose
    Recombinant Human PON3/Paraoxonase 3 Protein (50 Ser/Asn, His Tag)
    Sequence
    Met 1-Leu 354
    Characteristics
    A DNA sequence encoding the human PON3 (Q15166-1) (Met 1-Leu 354) (50 Ser/Asn) was expressed, with a polyhistidine tag at the N-terminus.
    Purity
    > 85 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg of the protein as determined by the LAL method.
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    Discover our top product PON3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 1 mM CaCL2, 10 % glycerol, 0.1 % DDM
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    PON3 (Paraoxonase 3 (PON3))
    Alternative Name
    PON3/Paraoxonase 3 (PON3 Products)
    Synonyms
    2810004E20 Protein, AI786302 Protein, paraoxonase 3 Protein, PON3 Protein, Pon3 Protein
    Background

    Background: KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.

    Synonym: PON3

    Molecular Weight
    42 kDa
    Pathways
    Monocarboxylic Acid Catabolic Process
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