Peroxiredoxin 1 Protein (PRDX1) (His tag)
Quick Overview for Peroxiredoxin 1 Protein (PRDX1) (His tag) (ABIN7318889)
Target
See all Peroxiredoxin 1 (PRDX1) ProteinsProtein Type
Origin
Source
Purity
-
-
Purification tag / Conjugate
- This Peroxiredoxin 1 protein is labelled with His tag.
-
Purpose
- Recombinant Human Peroxiredoxin 1/PRDX1 Protein (His Tag)
-
Sequence
- Met 1-Lys199
-
Characteristics
- Recombinant Human Peroxiredoxin-1 is produced by our E.coli expression system and the target gene encoding Met1-Lys199 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
-
Sterility
- 0.2 μm filtered
-
Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
-
Biological Activity Comment
- Not validated for activity
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
Peroxiredoxin 1 (PRDX1) (AA 1-199) (Active) protein (His tag)
PRDX1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS, EAA Active
Peroxiredoxin 1 (PRDX1) protein (His tag)PRDX1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
Peroxiredoxin 1 (PRDX1) (AA 1-199) protein (GST tag)PRDX1 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Peroxiredoxin 1 (PRDX1) (AA 1-199), (full length) protein (GST tag)PRDX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA
Peroxiredoxin 1 (PRDX1) protein (His tag,GST tag)PRDX1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB
Peroxiredoxin 1 (PRDX1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PRDX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Peroxiredoxin 1 (PRDX1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PRDX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, 0.1 mM DTT, pH 6.0.
-
Preservative
- Dithiothreitol (DTT)
-
Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
Expiry Date
- 6 months
-
-
- Peroxiredoxin 1 (PRDX1)
-
Alternative Name
- Peroxiredoxin 1/PRDX1
-
Background
- MSP23,NKEF-A,NKEFA,Natural killer cell-enhancing factor A,PAG,PAGA,PAGB,PRX1,PRXI,Peroxiredoxin-1,Proliferation-associated gene protein,TDPX2,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2,Peroxiredoxin-1(PRDX1) contains 1 thioredoxin domain and belongs to the AhpC/TSA family. PRDX1 constitutively expressed in most human cells and it is induced to higher levels upon serum stimulation in untransformed and transformed cells. PRDX1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and play an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. It may contribute to the antiviral activity of CD8(+) T-cells and have a proliferative effect in cancer development or progression.
-
Molecular Weight
-
Calculated MW: 25.3 kDa
Observed MW: 26 kDa
-
Gene ID
- 5052
-
UniProt
- Q06830
-
Pathways
- p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
Target
-
