RNASE6 Protein (AA 24-150) (His tag)

Catalog No. ABIN7318991

Recombinant RNASE6 protein expressed in HEK-293 Cells.

Quick Overview for RNASE6 Protein (AA 24-150) (His tag) (ABIN7318991)

Target: RNASE6 (Ribonuclease, RNase A Family, K6 (RNASE6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 24-150

Purification tag / Conjugate: This RNASE6 protein is labelled with His tag.

Purpose: Recombinant Human Ribonuclease K6/RNASE6 Protein (His Tag)

Sequence: Trp24-Leu150

Characteristics: Recombinant Human Ribonuclease K6 is produced by our Mammalian expression system and the target gene encoding Trp24-Leu150 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, 10 % Glycerol, pH 7.5.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: RNASE6 (Ribonuclease, RNase A Family, K6 (RNASE6))

Alternative Name: Ribonuclease K6/RNASE6

Background: RNASE6,RNS6,RNase K6,Ribonuclease K6,Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino acid mature chain. RNASE6 is expressed in many tissues, with high expression levels in the lung, with lower expression levels in the heart, placenta, kidney, pancreas, liver, brain, and skeletal muscle. It is also detected in monocytes and neutrophils. RNASE6 may have a role in host defense.

Molecular Weight:

Calculated MW: 15.7 kDa

Observed MW: 18-25 kDa

Gene ID: 6039

UniProt: Q93091