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SRGN Protein (His tag)

SRGN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317218
  • Target See all SRGN Proteins
    SRGN (serglycin (SRGN))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    • 1
    Human
    Source
    • 5
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SRGN protein is labelled with His tag.
    Purpose
    Recombinant Human Serglycin/SRGN Protein (His Tag)
    Sequence
    Met 1-Leu158
    Characteristics
    A DNA sequence encoding the human SRGN (CAA34900.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SRGN Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SRGN (serglycin (SRGN))
    Alternative Name
    Serglycin/SRGN (SRGN Products)
    Synonyms
    PPG Protein, PRG Protein, PRG1 Protein, Prg Protein, Prg1 Protein, Sgc Protein, Pgsg Protein, serglycin Protein, SRGN Protein, Srgn Protein
    Background

    Background: SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.

    Synonym: PPG,PRG,PRG1

    Molecular Weight
    16.1 kDa
    Pathways
    Maintenance of Protein Location
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