SRGN Protein (His-Myc tag)

Catalog No. ABIN7317217

This Recombinant SRGN protein is expressed in HEK-293 Cells.

Quick Overview for SRGN Protein (His-Myc tag) (ABIN7317217)

Target: SRGN (serglycin (SRGN))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 90 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This SRGN protein is labelled with His-Myc tag.

Purpose: Recombinant Human Serglycin/SRGN Protein (His&Myc Tag)

Sequence: Met 1-Leu158

Characteristics: A DNA sequence encoding the human SRGN (Met1-Leu158) was fused with the C-terminal polyhistidine-tagged myc at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: SRGN (serglycin (SRGN))

Alternative Name: Serglycin/SRGN

Background: PPG,PRG,PRG1,SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.

Molecular Weight:

Calculated MW: 17.3 kDa

Observed MW: 27 kDa

Gene ID: 5552

UniProt: P10124

Pathways: Maintenance of Protein Location