SERPINB12 Protein (His tag)

Catalog No. ABIN7319018

This Recombinant SERPINB12 protein is produced in HEK-293 Cells.

Quick Overview for SERPINB12 Protein (His tag) (ABIN7319018)

Target: SERPINB12 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 12 (SERPINB12))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This SERPINB12 protein is labelled with His tag.

Purpose: Recombinant Human SerpinB12/SERPINB12 Protein (His Tag)

Sequence: Met 1-Pro425

Characteristics: Recombinant Human Serine Protease Inhibitor-clade B12 is produced by our Mammalian expression system and the target gene encoding Met1-Pro425 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 10 % Trehalose, 0.05 % Tween 80, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: SERPINB12 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 12 (SERPINB12))

Alternative Name: SerpinB12/SERPINB12

Background: SERPINB12,Serine Protease Inhibitor-clade B12,Serpin B12,Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. SerpinB12 inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.

Molecular Weight:

Calculated MW: 49.5 kDa

Observed MW: 55 kDa

UniProt: Q3SYB4