SERPINB12 Protein (His tag)

Catalog No. ABIN7320232

This Recombinant SERPINB12 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for SERPINB12 Protein (His tag) (ABIN7320232)

Target: SERPINB12 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 12 (SERPINB12))

Protein Type: Recombinant

Origin: Mouse

Source: Baculovirus infected Insect Cells

Purity: > 92 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This SERPINB12 protein is labelled with His tag.

Purpose: Recombinant Mouse SerpinB12/SERPINB12 Protein (His Tag)

Sequence: Met 1-Pro 423

Characteristics: A DNA sequence encoding the mouse SERPINB12 (NP_082247.1) (Met 1-Pro 423) was expressed, with a C-terminal polyhistidine tag.

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 10 % glycerol, pH 7.4

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: SERPINB12 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 12 (SERPINB12))

Alternative Name: SerpinB12/SERPINB12

Background:

Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Mouse SerpinB12 is a cytoplasm protein which belongs to the serpin family and Ov-serpin subfamily. It is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. SerpinB12 inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.

Synonym: 2300003F07Rik;4833409F13Rik

Molecular Weight: 49.3 kDa

NCBI Accession: NP_082247