Quick Overview for SNCA Protein (ABIN7320688)
Target
See all SNCA ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Mouse α-Synuclein/SNCA Protein
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Sequence
- Met1-Ala140
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Characteristics
- Recombinant Mouse alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Synuclein, alpha (SNCA) (A53T) (Active) protein
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (His-IF2DI Tag)SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) proteinSNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SNCA (Synuclein, alpha (SNCA))
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Alternative Name
- alpha-Synuclein/SNCA
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Background
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Background: Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).
Synonym: Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, Snca
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Molecular Weight
- 14.5 kDa
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UniProt
- O55042
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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