TXN2 Protein (AA 60-166)

Catalog No. ABIN7319080

This Recombinant TXN2 protein is produced in Escherichia coli (E. coli).

Quick Overview for TXN2 Protein (AA 60-166) (ABIN7319080)

Target: TXN2 (Thioredoxin 2 (TXN2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 60-166

Purpose: Recombinant Human Thioredoxin-2/TXN2 Protein

Sequence: Thr60-Gly166

Characteristics: Recombinant Human Thioredoxin-2 is produced by our E.coli expression system and the target gene encoding Thr60-Gly166 is expressed with a 6His tag at the N-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: TXN2 (Thioredoxin 2 (TXN2))

Alternative Name: Thioredoxin-2/TXN2

Background: MTRX,Mt-Trx,TRX2,TXN2,Thioredoxin Mitochondrial,Thioredoxin-2,Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide, which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition, Thioredoxin-2 is important at low oxidative stress conditions.

Molecular Weight:

Calculated MW: 12.0 kDa

Observed MW: 13 kDa

Gene ID: 25828

UniProt: Q99757

Pathways: Cell RedoxHomeostasis