Quick Overview for ACE2 Protein (Fc Tag) (ABIN7321044)
Target
See all ACE2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purification tag / Conjugate
- This ACE2 protein is labelled with Fc Tag.
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Purpose
- Recombinant Rhesus Macaque Angiotensin-Converting Enzyme 2/ACE-2 (C-Fc)
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Sequence
- Gln18-Val739
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Characteristics
- Recombinant Rhesus Macaque Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Val739 is expressed with a Fc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Immobilized 2019-nCoV S Protein RBD-SD1-mFc(Cat#PKSR030476)at 2μg/ml (100 μl/well) can bind Rhesus Macaque ACE-2-Fc(Cat#PKSQ050120).The ED50 of Recombinant Rhesus Macaque ACE-2-His(Cat#PKSQ050120)is 96 ng/ml.
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Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag,AVI tag,Biotin)
ACE2 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS, Func
Angiotensin I Converting Enzyme 2 (ACE2) protein (His tag)ACE2 Origin: Paguma larvata Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. SDS
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (Biotin,His-Avi Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-739) (Active) protein (His-Avi Tag)ACE2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (hFc-Avi Tag,Biotin)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (His-Avi Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Angiotensin I Converting Enzyme 2 (ACE2) (Active) protein (His tag)ACE2 Origin: Rhesus Monkey Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) (Active) protein (Fc Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. SDS, Func Active
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (His tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-740) protein (mFc Tag)ACE2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Comment
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120-140 kDa
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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Alternative Name
- ACE-2
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Background
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Background: Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Synonym: Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2
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Molecular Weight
- 110.6 kDa
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Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Target
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