Quick Overview for VTCN1 Protein (His tag) (ABIN7321009)
Target
See all VTCN1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
-
-
Purification tag / Conjugate
- This VTCN1 protein is labelled with His tag.
-
Purpose
- Recombinant Rhesus macaque B7-H4/VTCN1 Protein (His Tag)
-
Sequence
- Phe29-Ala258
-
Characteristics
- Recombinant Rhesus macaque B7-H4 is produced by our Mammalian expression system and the target gene encoding Phe29-Ala258 is expressed with a 6His tag at the C-terminus.
-
Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
-
Biological Activity Comment
- Immobilized Human GFRA1-His(Cat: PKSH033670) at 0.5μg/ml(100 μl/well) can bind Human GDNF. The ED50 of GDNF is 14.73ug/ml.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 29-258) protein (His-Avi Tag)
VTCN1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 29-258) (Active) protein (Biotin,His-Avi Tag)VTCN1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 29-258) (Active) protein (His tag)VTCN1 Origin: Rhesus Monkey, Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-191) (Active) protein (His tag)VTCN1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-194) (Active) protein (hFc Tag)VTCN1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 33-194) protein (Fc Tag)VTCN1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (Active) protein (Biotin)VTCN1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 29-256) protein (His tag)VTCN1 Origin: Mouse Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 31-258) protein (His-IF2DI Tag)VTCN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 25-259) protein (His tag)VTCN1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % SDS
-
-
Comment
-
40-60 kDa
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Please refer to the printed manual for detailed information.
-
Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
-
Storage
- 4 °C,-20 °C,-80 °C
-
Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
-
Alternative Name
- B7-H4/VTCN1
-
Background
-
Background: B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Synonym: B7S1, B7x, Vtcn1, B7h.5, B7-H4, B7H4T-cell costimulatory molecule B7x, B7S1VCTN1, B7XPRO1291, FLJ22418, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, V-set domain containing T cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1
-
Molecular Weight
- 26.4 kDa
-
UniProt
- F7B770
Target
-
