C5A Protein (AA 678-751) (His tag)

Catalog No. ABIN7274012

Recombinant C5A protein expressed in Escherichia coli (E. coli).

Quick Overview for C5A Protein (AA 678-751) (His tag) (ABIN7274012)

Target: C5A (C5a) (Complement Component 5a (C5a))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by Bis-Tris PAGE

Product Details

Protein Characteristics: AA 678-751

Purification tag / Conjugate: This C5A protein is labelled with His tag.

Purpose: Human Complement C5a Protein

Sequence: Thr678-Arg751

Characteristics: Recombinant Human C5a Protein is expressed from E.coli with His tag at the N-Terminus.It contains Thr678-Arg751.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Human C5a on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl, 10 % Glycerol ( pH 7.4).

Storage: -80 °C

Storage Comment: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: C5A (C5a) (Complement Component 5a (C5a))

Alternative Name: C5a

Background: The anaphylatoxin C5a is an extremely potent proinflammatory peptide produced during activation of the complement system. The structure of C5a includes a core region (N-terminal residues 1-63) consisting of four, antiparallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail (residues 64-74).

Molecular Weight: 9.37 kDa. The protein migrates to 13-14 kDa based on Bis-Tris PAGE result.

UniProt: P01031

Pathways: Complement System, Carbohydrate Homeostasis