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CDCP1 Protein (AA 29-667) (His tag)

CDCP1 Origin: Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274291
  • Target See all CDCP1 Proteins
    CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-667
    Origin
    • 15
    • 4
    • 1
    • 1
    • 1
    Rhesus Monkey
    Source
    • 15
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CDCP1 protein is labelled with His tag.
    Purpose
    Rhesus macaque CDCP1 Protein
    Sequence
    Ala29-Thr667
    Characteristics
    Recombinant Rhesus macaque CDCP1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala29-Thr667.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Cynomolgus CDCP1 at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CDCP1 Ab., hFc Tag with the EC50 of 23.7ng/ml determined by ELISA. See testing image for detail.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CDCP1 (CUB Domain Containing Protein 1 (CDCP1))
    Alternative Name
    CDCP1 (CDCP1 Products)
    Background
    Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
    Molecular Weight
    73.2 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    XP_001114659
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