GUCY2C Protein (AA 21-430) (His tag)
Quick Overview for GUCY2C Protein (AA 21-430) (His tag) (ABIN7274714)
Target
See all GUCY2C ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 21-430
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Purification tag / Conjugate
- This GUCY2C protein is labelled with His tag.
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Purpose
- Canine GUCY2C/Guanylyl cyclase C Protein
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Sequence
- Tyr21-Gln430
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Characteristics
- Recombinant Canine GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr21-Gln430.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per ug by the LAL method.
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Biological Activity Comment
- Canine GUCY2C/Guanylyl cyclase C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Canine GUCY2C/Guanylyl cyclase C is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))
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Alternative Name
- GUCY2C
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Background
- Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
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Molecular Weight
- 47.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.
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UniProt
- F1PAG3
Target
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