GUCY2C Protein (AA 24-430) (His tag)
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- Target See all GUCY2C Proteins
- GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 24-430
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GUCY2C protein is labelled with His tag.
- Characteristics
- Cynomolgus GUCY2C / Guanylyl cyclase C Protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GUCY2C Protein
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Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (His-Avi Tag,Biotin)
GUCY2C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (Fc Tag)GUCY2C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) protein (His-Avi Tag)GUCY2C Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (His tag)GUCY2C Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 21-430) protein (His tag)GUCY2C Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) (Active) protein (His tag,AVI tag,Biotin)GUCY2C Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) (Active) protein (Fc Tag,AVI tag,Biotin)GUCY2C Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-133) protein (GST tag)GUCY2C Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 24-430) protein (His tag)Crystallography grade GUCY2C Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C) (AA 20-433) protein (His tag)Crystallography grade GUCY2C Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))
- Alternative Name
- GUCY2C (GUCY2C Products)
- Synonyms
- DIAR6 Protein, GUC2C Protein, MECIL Protein, MUCIL Protein, STAR Protein, AI893437 Protein, GC-C Protein, Gcc Protein, GCC Protein, gucy2c-A Protein, GUCY2C Protein, Gucy2c Protein, guanylate cyclase 2C Protein, guanylate cyclase 2c Protein, guanylate cyclase 2C L homeolog Protein, GUCY2C Protein, Gucy2c Protein, gucy2c.L Protein, gucy2c Protein
- Background
- GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.
- Molecular Weight
- 48.0 kDa
- NCBI Accession
- XP_005570270
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