ERBB3 Protein (AA 20-643) (Fc Tag)
Quick Overview for ERBB3 Protein (AA 20-643) (Fc Tag) (ABIN7274797)
Target
See all ERBB3 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 20-643
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Purification tag / Conjugate
- This ERBB3 protein is labelled with Fc Tag.
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Purpose
- Human Her3/ErbB3 Protein
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Sequence
- Ser20-Thr643
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Characteristics
- Recombinant Human Her3/ErbB3 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser20-Thr643.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human Her3, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-Her3 Antibody, hFc Tag with the EC50 of 13.5ng/ml determined by ELISA. See testing image for detail.
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Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-643) protein (His-Avi Tag)
ERBB3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-641) protein (His tag)ERBB3 Origin: Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-643) protein (His tag)ERBB3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 20-643) protein (His-Avi Tag,Biotin)ERBB3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 544-643) protein (mFc Tag)ERBB3 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 544-643) protein (Fc Tag)ERBB3 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1005-1230) protein (His tag)ERBB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 21-331) protein (GST tag)ERBB3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (Active) protein (His tag)ERBB3 Origin: Mouse Host: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE Active
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) protein (Biotin,His-Avi Tag)ERBB3 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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Alternative Name
- Her3
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Background
- Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
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Molecular Weight
- 95.4 kDa. Due to glycosylation, the protein migrates to 110-120 kDa based on Tris-Bis PAGE result.
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UniProt
- P21860
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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