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IL15RA Protein (AA 31-205) (Fc Tag)

IL15RA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7275020
  • Target See all IL15RA Proteins
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 31-205
    Origin
    • 13
    • 4
    • 1
    Human
    Source
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL15RA protein is labelled with Fc Tag.
    Purpose
    Human IL-15RA/IL-15 R alpha/CD215 Protein
    Sequence
    Ile31-Thr205
    Characteristics
    Recombinant Human IL-15RA/IL-15 R alpha/CD215 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile31-Thr205.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-15, No Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-15RA, hFc Tag with the EC50 of 61.2ng/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
    Alternative Name
    IL-15RA (IL15RA Products)
    Background
    Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development.
    Molecular Weight
    45.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
    UniProt
    Q13261-1
    Pathways
    JAK-STAT Signaling
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