Midkine Protein (AA 23-140) (His tag)
Quick Overview for Midkine Protein (AA 23-140) (His tag) (ABIN7275260)
Target
See all Midkine (MDK) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 23-140
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Purification tag / Conjugate
- This Midkine protein is labelled with His tag.
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Purpose
- Mouse Midkine Protein
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Sequence
- Lys23-Asp140
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Characteristics
- Recombinant Mouse Midkine Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys23-Asp140.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse Midkine on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS, 350 mM NaCl, 200 mM L-arginine ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
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Alternative Name
- Midkine
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Background
- Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis.
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Molecular Weight
- 14.03 kDa. The protein migrates to 18-23 kDa based on Bis-Tris PAGE result.
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UniProt
- P12025
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Pathways
- RTK Signaling, M Phase, Skeletal Muscle Fiber Development
Target
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