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SIGLEC15 Protein (AA 24-262) (Biotin,His tag)

This Recombinant SIGLEC15 protein is produced in HEK-293 Cells.
Catalog No. ABIN7275615
$715.42
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Quick Overview for SIGLEC15 Protein (AA 24-262) (Biotin,His tag) (ABIN7275615)

Target

See all SIGLEC15 Proteins
SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 13
  • 7
  • 6
Mouse

Source

  • 15
  • 5
  • 4
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Bis-Tris PAGE
  • Protein Characteristics

    AA 24-262

    Purification tag / Conjugate

    This SIGLEC15 protein is labelled with Biotin,His tag.

    Purpose

    Biotinylated Mouse Siglec-15/CD33L3 Protein (Primary Amine Labeling)

    Sequence

    Arg24-Thr262

    Characteristics

    Recombinant Biotinylated Mouse Siglec-15/CD33L3 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Arg24-Thr262.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Biotinylated Mouse Siglec-15/CD33L3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Supplied as 0.22μm filtered solution in 20 mM PB, 0.5M NaCl, 0.1M L-arginine ( pH 7.4).

    Storage

    -80 °C

    Storage Comment

    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))

    Alternative Name

    Siglec-15

    Background

    Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.

    Molecular Weight

    26.7 kDa. Due to glycosylation, the protein migrates to 35-43 kDa based on Bis-Tris PAGE result.

    UniProt

    A7E1W8
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