SIGLEC15 Protein (AA 24-262) (Biotin,His tag)
Quick Overview for SIGLEC15 Protein (AA 24-262) (Biotin,His tag) (ABIN7275615)
Target
See all SIGLEC15 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 24-262
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Purification tag / Conjugate
- This SIGLEC15 protein is labelled with Biotin,His tag.
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Purpose
- Biotinylated Mouse Siglec-15/CD33L3 Protein (Primary Amine Labeling)
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Sequence
- Arg24-Thr262
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Characteristics
- Recombinant Biotinylated Mouse Siglec-15/CD33L3 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Arg24-Thr262.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Biotinylated Mouse Siglec-15/CD33L3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in 20 mM PB, 0.5M NaCl, 0.1M L-arginine ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
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Alternative Name
- Siglec-15
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Background
- Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
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Molecular Weight
- 26.7 kDa. Due to glycosylation, the protein migrates to 35-43 kDa based on Bis-Tris PAGE result.
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UniProt
- A7E1W8
Target
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