TLR3 Protein (AA 23-703) (His tag,Biotin)
Quick Overview for TLR3 Protein (AA 23-703) (His tag,Biotin) (ABIN7275747)
Target
See all TLR3 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 23-703
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Purification tag / Conjugate
- This TLR3 protein is labelled with His tag,Biotin.
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Purpose
- Biotinylated Human TLR3 Protein (Primary Amine Labeling)
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Sequence
- Ser23-Glu703
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Characteristics
- Recombinant Biotinylated Human TLR3 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser23-Glu703.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Toll-Like Receptor 3 (TLR3) (AA 23-703) (Active) protein (His tag)
TLR3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Toll-Like Receptor 3 (TLR3) (AA 26-705) (Active) protein (His tag)TLR3 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Toll-Like Receptor 3 (TLR3) (AA 31-711) (Active) protein (His tag)TLR3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Toll-Like Receptor 3 (TLR3) (AA 601-700) protein (GST tag)TLR3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Toll-Like Receptor 3 (TLR3) protein (His tag)TLR3 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Toll-Like Receptor 3 (TLR3) (AA 24-704) protein (Fc Tag)TLR3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Toll-Like Receptor 3 (TLR3) (AA 24-704) protein (mFc Tag)TLR3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Toll-Like Receptor 3 (TLR3) (AA 24-704) protein (His tag)TLR3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- TLR3 (Toll-Like Receptor 3 (TLR3))
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Alternative Name
- TLR3
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Background
- TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.
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Molecular Weight
- 78.7 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.
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UniProt
- Q6PCD4
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Pathways
- TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Target
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