CD28 Protein (CD28) (His tag)
Quick Overview for CD28 Protein (CD28) (His tag) (ABIN7447918)
Target
See all CD28 ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CD28 protein is labelled with His tag.
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Purpose
- Rat CD28 Protein, His Tag (BLI verified)
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Sequence
- Asn 20 - Leu 150
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Characteristics
- Rat CD28, His Tag is expressed from human 293 cells (HEK293). It contains AA Asn 20 - Leu 150 (Accession # P31042-1).
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Endotoxin Level
- 1.0 EU per μg
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CD28 (CD28) (AA 19-152) protein (His-Avi Tag)
CD28 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD28 (CD28) (AA 19-152) protein (His-Avi Tag,Biotin)CD28 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD28 (CD28) (AA 19-152) protein (mFc-His Tag)CD28 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA, FACS
CD28 (CD28) (AA 19-152) protein (Fc Tag)CD28 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD28 (CD28) (AA 19-152) (Active) protein (Fc Tag)CD28 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD28 (CD28) (AA 19-152) (Active) protein (Fc Tag,AVI tag,Biotin)CD28 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD28 (CD28) (Active) protein (His tag)CD28 Origin: Human, Cynomolgus Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
CD28 (CD28) (AA 19-152) protein (mFc Tag)CD28 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD28 (CD28) (AA 18-153) protein (mFc Tag)CD28 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD28 (CD28) (AA 18-153) protein (His tag)CD28 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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Comment
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.9 kDa. The protein migrates as 30-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- CD28
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Alternative Name
- CD28
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Background
- Synonyms:CD28,Tp44,Description:T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
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Molecular Weight
- 16.9 kDa
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NCBI Accession
- NP_037253
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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