SNCA Protein (AA 1-140)
Quick Overview for SNCA Protein (AA 1-140) (ABIN7504231)
Target
See all SNCA ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-140
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Purpose
- Human Alpha Synuclein Protein
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Sequence
- Met1-Ala140
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Characteristics
- Recombinant Human Alpha Synuclein Protein is expressed from E.coli without tag.It contains Met1-Ala140.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- SNCA (Synuclein, alpha (SNCA))
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Alternative Name
- Alpha Synuclein
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Background
- Alpha-synuclein (α-synuclein) is a small, acidic protein containing 140 amino acids, highly expressed in the brain and primarily localized in the presynaptic terminals. It is found in high concentrations in Lewy Bodies, proteinaceous aggregates that constitute a typical histopathologic hallmark of Parkinson's disease.
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Molecular Weight
- 14.5 kDa same as Tris-Bis PAGE result.
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UniProt
- P37840-1
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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