BDNF Protein (AA 129-247)

Catalog No. ABIN7504243

This Recombinant BDNF protein is expressed in Escherichia coli (E. coli).

Quick Overview for BDNF Protein (AA 129-247) (ABIN7504243)

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Protein Type: Recombinant

Origin: Human, Rat, Mouse

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by Tris-Bis PAGE

Product Details

Protein Characteristics: AA 129-247

Purpose: Human/Murine/Rat BDNF Protein

Sequence: His129-Arg247

Characteristics: Recombinant Human/Murine/Rat BDNF Protein is expressed from E.coli without tagIt contains His129-Arg247.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 0.01 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Alternative Name: BDNF

Background: The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. Brain-derived neurotrophic factor biosynthesis and secretion are chrono-topically regulated processes at the cellular level, accounting for specific localizations and functions.

Molecular Weight: 13.51 kDa. The protein migrates to 15-19 kDa based on Tris-Bis PAGE result.

UniProt: P23560-1

Pathways: RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity