PAI1 Protein (AA 24-402) (His tag)
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- Target See all PAI1 (SERPINE1) Proteins
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-402
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PAI1 protein is labelled with His tag.
- Sequence
- Ser 24-Pro 402
- Characteristics
- A DNA sequence encoding the Rat PAI-1/ SerpinE1 protein (P20961) (Ser 24-Pro 402) was expressed with N-His tag.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- Alternative Name
- PAI-1 (SERPINE1 Products)
- Background
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Abbreviation: PAI-1,SerpinE1
Target Synonym: Plasminogen activator inhibitor 1,Endothelial plasminogen activator inhibitor,Serpin E1,Mr1,Pai1,Planh1
Background: Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
- Molecular Weight
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Calculated MW: 41.58 kDa
Observed MW: 42 kDa
- UniProt
- P20961
- Pathways
- p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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