Angiopoietin 1 Protein (ANGPT1) (His tag)
Quick Overview for Angiopoietin 1 Protein (ANGPT1) (His tag) (ABIN7536327)
Target
See all Angiopoietin 1 (ANGPT1) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Angiopoietin 1 protein is labelled with His tag.
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Purpose
- Recombinant Mouse Angiopoietin-1/ANG-1/ANGPT1 Protein
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Sequence
- REEEKPFRDC ADVYQAGFNK SGIYTIYFNN MPEPKKVFCN MDVNGGGWTV IQHREDGSLD FQRGWKEYKM GFGNPSGEYW LGNEFIFAIT SQRQYMLRIE LMDWEGNRAY SQYDRFHIGN EKQNYRLYLK GHTGTAGKQS SLILHGADFS TKDADNDNCM CKCALMLTGG WWFDACGPSN LNGMFYTAGQ NHGKLNGIKW HYFKGPSYSL RSTTMMIRPL DF
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Specificity
- Arg277-Phe498
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- <0.001EU/μg
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Angiopoietin 1 (ANGPT1) protein (Fc Tag)
ANGPT1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Angiopoietin 1 (ANGPT1) (AA 1-498) protein (GST tag)ANGPT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiopoietin 1 (ANGPT1) (AA 20-498) proteinANGPT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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Concentration
- 0.92 mg/mL
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Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Angiopoietin 1 (ANGPT1)
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Alternative Name
- Angiopoietin-1/ANG-1/ANGPT1
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Background
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Description: The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis.
Name: Ang1, Ang-1, 1110046O21Rik
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Gene ID
- 11600
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UniProt
- O08538
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Pathways
- RTK Signaling, Glycosaminoglycan Metabolic Process
Target
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