Angiopoietin 1 Protein (ANGPT1) (His tag)
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- Target See all Angiopoietin 1 (ANGPT1) Proteins
- Angiopoietin 1 (ANGPT1)
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Angiopoietin 1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse Angiopoietin-1/ANG-1/ANGPT1 Protein
- Sequence
- REEEKPFRDC ADVYQAGFNK SGIYTIYFNN MPEPKKVFCN MDVNGGGWTV IQHREDGSLD FQRGWKEYKM GFGNPSGEYW LGNEFIFAIT SQRQYMLRIE LMDWEGNRAY SQYDRFHIGN EKQNYRLYLK GHTGTAGKQS SLILHGADFS TKDADNDNCM CKCALMLTGG WWFDACGPSN LNGMFYTAGQ NHGKLNGIKW HYFKGPSYSL RSTTMMIRPL DF
- Specificity
- Arg277-Phe498
- Purity
- > 97 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- <0.001EU/μg
- Top Product
- Discover our top product ANGPT1 Protein
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Angiopoietin 1 (ANGPT1) (AA 1-498) protein (GST tag)
ANGPT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiopoietin 1 (ANGPT1) (AA 221-320) protein (GST tag)ANGPT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Angiopoietin 1 (ANGPT1) protein (Fc Tag)ANGPT1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Concentration
- 0.92 mg/mL
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Target
- Angiopoietin 1 (ANGPT1)
- Alternative Name
- Angiopoietin-1/ANG-1/ANGPT1 (ANGPT1 Products)
- Synonyms
- AGP1 Protein, AGPT Protein, ANG1 Protein, 1110046O21Rik Protein, Ang-1 Protein, Ang1 Protein, Agpt Protein, Agpt1 Protein, ang1 Protein, wu:fc76g06 Protein, ANG-1 Protein, angpt1 Protein, MGC80788 Protein, angiopoietin 1 Protein, angiopoietin 1 S homeolog Protein, ANGPT1 Protein, Angpt1 Protein, angpt1 Protein, angpt1.S Protein
- Background
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Description: The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis.
Name: Ang1, Ang-1, 1110046O21Rik
- Gene ID
- 11600
- UniProt
- O08538
- Pathways
- RTK Signaling, Glycosaminoglycan Metabolic Process
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